Heart - Alone Extra Quality
"Love Bug Leave My Heart Alone" is a 1967 single released by Motown girl group Martha and the Vandellas. The song's production was a departure from the Vandellas' repertoire as their label, Motown, was having a harder time staying with the times in the music industry and having a much harder time finding a hit for its acts after several departures including Vandellas collaborators William "Mickey" Stevenson and Holland-Dozier-Holland, who produced the b-side to this single, "One Way Out", one of the trio's final recordings with the Vandellas. Produced by Richard Morris, the song displayed of the narrator wanting "the love bug" (i.e., her former lover) to leave her alone so she won't "fall in love". The narrator, lead singer Martha Reeves, was left heart-broken the last time she allowed the man to come back to her but after suffering heartbreak, she expresses her disgust at the man's attempts, with her fellow members Rosalind Ashford and Betty Kelley chanting "get outta there, love bug, leave my heart alone". The song (with its unusual-for-Motown fuzz guitar) was their second consecutive Top 40 single of 1967 peaking at number twenty-five on the Billboard pop singles chart and number fourteen on the Billboard Hot R&B singles chart. The record was the first track ever played on UK Radio One by DJ John Peel.
Heart - Alone
Despite these advances, smoking remains a critical threat to the validity of findings concerning periodontal infection and AVD. Nevertheless, it is clear that the preponderance of evidence to date in support of a positive association between periodontal infection and CVD cannot be completely explained by smoking, and therefore exists independent of smoking behaviors. With an example from the cancer epidemiology literature, it has been convincingly demonstrated that it is unrealistic to conclude that smoking alone, particularly residual confounding by smoking or environmental tobacco smoke, can completely explain the reported associations in observational epidemiological studies (Michaud et al., 2007; Taguchi, 2007). Nevertheless, future research can benefit from careful methodological work with specific focus on confounding using modern epidemiological tools such as Directed Acyclic Graphs (DAGs) (Merchant and Pitiphat, 2002), which provide a quick visual method for the selection of potential confounders and minimization of bias in the design and analysis of epidemiological studies.
Going beyond clinical definitions, several studies described above have used assessments of periodontal bacterial colonization as exposures associated with subclinical AVD (Desvarieux et al., 2005) or coronary heart disease outcomes (Renvert et al., 2006; Spahr et al., 2006; Nonnenmacher et al., 2007). No data are so far available addressing the association between colonization levels and stroke outcomes. Alternatively, at least 11 studies have now been published using serum antibody responses to periodontal bacteria as the main exposure of interest (Pussinen et al., 2003, 2004a,b, 2005, 2007a,b; Taniguchi et al., 2003; Beck et al., 2005a,b; Johansson et al., 2005; Lund Håheim et al., 2008). A meta-analysis including several of these studies (Mustapha et al., 2007) reported the overall trend to suggest a 36% increased risk for CVD outcomes associated with elevated systemic antibody responses, although the summary measure was not statistically significant (p = 0.09). When only CHD outcomes were considered, the findings were stronger and statistically significant: odds ratio 1.75 (95% CI, 1.32 to 2.34; p
Recent human in vivo studies support and extend these observations. A comparison of platelet-activating factor (PAF) levels in sera and GCF from patients with periodontitis, patients with coronary heart disease (CHD) without periodontitis, patients with periodontitis and CHD, and healthy control individuals showed significantly higher serum and GCF levels in all patient groups when compared with levels in control individuals (Chen et al., 2009). In another case-control study (Papapanagiotou et al., 2009), significantly elevated soluble P-selectin, a marker of platelet activation, was documented in the plasma of patients when compared with periodontitis-free control individuals. Furthermore, platelets from periodontitis patients showed an increased binding of the glycoprotein IIb-IIIa complex, a direct measure of platelet activation, which correlated positively with the extent and severity of periodontitis of the donor. The same research group (Nicu et al., 2009) stimulated platelets and leukocytes from periodontitis patients and periodontally healthy control individuals with four oral bacteria (A. actinomycetemcomitans, P. gingivalis, Tannerella forsythia, and Streptococcus sanguis) and reported higher platelet expression of P-selectin, and increased formation of platelet-monocyte complexes in periodontitis donors. Furthermore, platelet/monocyte complexes displayed a better ability to bind and phagocytose A. actinomycetemcomitans, suggesting that increased atherothrombosis was paralleled by enhanced bacterial clearance.
Background: Anemia is common in patients with CHF and is associated with higher morbidity and mortality. The combination of erythropoietin (EPO) and iron increases hemoglobin (Hb) and improves symptoms and exercise capacity in anemic CHF patients. It is not known whether intravenous iron alone is an effective treatment for anemia associated with CHF.
Forever taking it on the chin (do not go there), those sweet Wilson sisters deserve a break. First, early in their career, there was that cheesy ad campaign implying the sibs were engaged in incestuous lezbionic relations (see above), then throughout the Eighties, can we talk about all that body-shaming of lead singer Ann? (From mostly paunchy, bald white dude rock critics?) And then there was that whole Sarah "Barracuda" thing in the 2008 election. Seriously, cut them a break. No matter how you might feel about them or their music, chances are, you never made Robert Plant cry. Poo Poo Platter will do their best this week to send them up and lay them out at the Hail Yasss: Raging Heart On, but we have a feeling whatever cruelty may be on tap will be delivered with open (albeit garroted) hearts and bled out in a big gooey puddle of plasmic love. (See Friday.)
HAIL YASSS: RAGING HEART ON Poo Poo Platter lays out a heartfelt tribute to the sisters Wilson and gets all "Barracuda" on yo ass. Fri., Nov. 13, 10pm. Elysium, 705 Red River. $5. www.fb.com/poopooatx.
Simultaneous heart and kidney transplantation delivers better survival for dialysis- and nondialysis-dependent recipients up to a glomerular filtration rate (GFR) of approximately 30 mL/min/1.73 m2 compared with heart transplantation alone, a study has shown.
Using the United Network for Organ Sharing registry, the authors compared long-term mortality between recipients with kidney dysfunction who underwent heart-kidney transplantation (n= 1,124) and those who had isolated heart transplantation (n=12,415) in the US between 2005 and 2018. Among patients who received heart-kidney transplants, contralateral kidney recipients were compared for allograft loss. Finally, the authors used multivariable Cox regression for risk adjustment.
Most of the time, heart attacks start slowly with just mild discomfort and pain, giving warning signs before they strike. If you experience any of the following symptoms, call 911 or ask someone to call 911 immediately.
If others are around, tell them to stay with you until emergency medical services (EMS) workers arrive. Calling 911 is usually the fastest way to get emergency care, as opposed to asking someone to drive you to a hospital in their car. EMS workers are trained to revive people experiencing heart attacks and can also transport you to the hospital for rapid care.
One type of treatment found online is called cough CPR. Some online sources claim that breathing deeply, and then coughing deeply, can raise your blood pressure for a second or two. Sources say this can deliver more blood to your brain. The claim also says that if your heart is beating normally, a deep cough may be able to set it back to normal.
Researchers say the results suggest that doctors should take a patient's living situation as well as age and other established risk factors into account when assessing his or her risk of heart disease.
They say certain heart disease risk factors may be more common in the lifestyles of people who live alone, such as obesity, smoking, high cholesterol, and making fewer visits to the family doctor, and may help explain the findings.
During a two-year period, 646 people were diagnosed with heart attack, severe chest pain (angina), or sudden cardiac death. These three manifestations of heart disease are part of a spectrum of conditions known as acute coronary syndrome.
For example, women over age 60 who lived alone comprised only about 5% of the study participants but accounted for a third of all deaths. Meanwhile, men over 50 who lived alone comprised under 8% of the study participants and accounted for two-thirds of the heart-related deaths.
As knowledge and technology advances, the need to identify objective measures for optimal classification of heart failure patients has become a focal point of many research endeavors. Among the long-time staples which have seen their utility questioned recently are ejection fraction and, now, NYHA class.
Further analysis indicated those classified as having NYHA class III heart failure had a greater rate of cardiovascular events compared to those with NYHA class I (HR, 1.84 [95% CI, 1.44-2.37]) or class II heart failure (HR, 1.49 [95% CI, 1.35-1.64]). Those in NYHA class I had a lower rate of events than those in NYHA class II (HR, 1.24 [95% CI, 0.97-1.58]). Before concluding, investigators pointed out stratification into subgroups defined by NT-proBNP levels identified subgroups of patients with distinctive cardiovascular risk. Underlining this distinctive risk, investigators highlighted results suggesting patients with NYHA class I heart failure with high NT-proBNP levels had a numerically higher event rate than patients with low NT-proBNP from any NYHA class (vs I, HR, 3.43 [95% CI, 2.03-5.87]; vs II, HR, 2.12 [95% CI, 1.58-2.86]; vs III, HR, 1.37 [95% CI, 1.00-1.88]). 041b061a72